Weight loss pill, How it works



you've been on the Internet before, and thus you've seen plenty of ads for treatments that will supposedly help you lose weight using one weird trick. Or you might have seen recent news about research claiming to have discovered what's been described as exercise in a pill. Sign me up. If those things really worked, I would be speaking for everybody when I said Shut up and take my money. Unfortunately, there's very little scientific evidence that any drug will make you lose weight in a significant amount safely and healthily. However, there really are some promising treatments in development right now that do at least something to help people lose weight based on new insights into how your body absorbs nutrients and uses energy. So sit down, enjoy your little bacon sandwich there while we walk you through the facts and fictions of weight loss in a pill. Let's start out with what your doctor could do for real today, because you actually can get medications for weight loss by prescription. And they come in two basic categories appetite suppressants and fat blockers. Appetite suppressants work by blocking your body's ability to reabsorb the chemical signals that your brain uses called neurotransmitters to regulate hunger. You've probably heard of a couple of these neurotransmitters, serotonin and norepinephrine. They are released by your hypothalamus to give a feeling that your not hungry. So if a chemical can block your body's ability to reabsorb those chemicals, you would feel more full and eat less. Do they work? Well, sort of an only for a while.
When combined with diet and exercise, studies have shown that prescription appetite suppressants can lead to losing around one and one half to maybe a little over two kilograms of extra weight. But after 6 to 8 weeks, the appetite control center in your brain adjusts to the new levels of these neurotransmitters, and the weight loss benefits disappear. Fat blockers work differently. They inhibit an enzyme known as lipase. When you eat food that has fat in it, those fat molecules need to be broken down into their constituent parts, glycerol and fatty acids before they can pass through the walls of your intestines. That's because fat molecules are too big to pass through the membranes of your cells on their own. Liposomes are the enzymes that break down those fat molecules, and in order to do that, they need to bind with the fat. Blocking drugs work by bonding with liposomes, which prevents them from bonding with fat and without liposomes to break it down. Fat passes through your intestines and out of your body without ever being absorbed. So do they work pretty well? Actually, studies have shown that they stop about 30% of the fat in your food from getting taken into your body. 

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